M03AC03 - Vecuronium |
Probably not porphyrinogenic |
PNP |
Rationale
Not metabolised. Two references consider it (probably) safe. Porphyrinogenic in rat model.
Chemical description
Aminosteroide muscle relaxant used under general anaesthesia. Excreted unchanged in bile and to a small extent in urine.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Induction of anaesthesia with etomidate in a patient with acute intermittent porphyria.
Famewo CE. Can Anaesth Soc J. 1985 Mar; 32(2):171-3.
|
3986654 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Vecuronium 
Bromuro Vecuronio Coll 
Norcuron · Vecuronium bromide 
Norcuron · Vecuronium 
Vecuronium 
Brocurix · Norcur · Vecuronio 
Norcuron · Vecure · Vecuronium 
Veculex 
Norcuron · Veculex · Vecuronium 
Vecuronium