M03AC09 - Rocuronium Bromide |
Not porphyrinogenic |
NP |
Rationale
Aminosteroide, structurally similar to pancurone. Probably not significantly metabolised. Two references consider it (probably) safe.
Chemical description
Aminosteroide muscle relaxant used in surgery. Partly excreted via bile. No metabolites have been identified in plasma or urine.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Sugammadex and amino acid infusion can contribute to safe anesthetic management of variegate porphyria.
Aoki Y, Atsumi K, et al. JA Clin Rep. 2018 Jun; 4(1):49.
|
32026031 |
| 2. | The use of rocuronium and sevoflurane in acute intermittent porphyria--a case report.
Hsieh CH, Hung PC, et al. Acta Anaesthesiol Taiwan. 2006 Sep; 44(3):169-71.
|
17037005 |
| Porphyria Drug Lists | ||
| 3. | French List
Centre Français des Porphyries
|
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| 4. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Esmeron · Rocuroniumbromide 
Esmeron · Rocuronium 
Esmeron · Rocuronio 
Esmeron · Rocuronium 
Esmeron · Rocuronio 
Esmeron · Rocuronium 
Esmeron · Rocuronium 
Esmeron · Rocuronium bromide 
Rocuronium 
Esmeron · Extempore M03AC09 Rokuroniumbromid · Rocuron · Rocuronium · Rocuroniumbromid · Rokuronbromid 
Esmeron · Rocuronium · Rokuroniumbromid 
Esmeron · Rocuronium · Roqurum 
Bromuro Rocuronio · Rocunium · Rocuronio · Rocuronio Bromuro · Rubidelt · Zemuroc 
Esmeron · Rocuronium 
Esmeron · Noveron · Rocuronium 
Rocuronium 
Esmeron · Rocuronium · Rocuroniumbromid 
Rocuronium 
Rocuronium 
Brometo Rocuronio · Esmeron · Rocuronio · Rocuronium · Rokuronijev · Roqurum 
Rocuronium 
Esmeron · Rocuronium 
Esmeron · Rocuronium · Rokuronijum 
Esmeron · Rokuronijev 
Esmeron · Rokuronijev 
Esmeron · Rocuronium · Rokuronium