N01AH01 - Fentanyl |
Probably not porphyrinogenic |
PNP |
Rationale
Substrate to, and inhibitor of CYP3A4. Administered in µg dose. Several references consider it safe for use.
Chemical description
Opioid analgesic used (50-100 µg/dose) intravenously in general anesthesia during long and moderately long surgery. Used together with droperidol in neuroleptanalgesia type II. Probably metabolized by CYP3A4.
IPNet drug reports
Uneventful use reported in 5 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Porphyrias.
James MF, Hift RJ. Br J Anaesth. 2000 Jul; 85(1):143-53.
|
10928003 |
| Porphyria Drug Lists | ||
| 2. | Australian List
Australian Porphyria Association No longer maintained
|
|
| 3. | French List
Centre Français des Porphyries
|
|
| 4. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 5. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Fentanyl 
Fentanyl 
Fentanest · Fentanilo 
Fentanyl 
Fentanest · Fentanil · Fentanyl 
Fentanil · Fentanyl 
Fentanyl 
Fentanyl · Sublimaze 
Fentanyl · Haldid 
Fentanilo · Fentanyl · Leptanal · Sublimaze 
Fentanyl 
Fentanyl 
Fentanex · Fentanilo · Fentanyl 
Fentanyl · Fentanyl GH 
Fentanyl 
Fentanyl 
Fentanyl 
Leptanal 
Fentanyl · Fentanyyli 
Fentanyl 
Fentanyl 
Fentanyl 
Fentanil · Fentanyl 
Fentanil · Fentanyl 
Fentanil · Fentanyl 
Fentanyl