N01AH02 - Alfentanil |
Probably not porphyrinogenic |
PNP |
Rationale
Administered only in 1 mg-dose. Metabolised by CYP3A4. Considered safe for use in references..
Chemical description
Opioid analgesic, chemically related to fentanyl, used (1 mg/dose) for general anesthesia in short and moderately short surgery. Extensively metabolized by CYP3A4 in the liver.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Porphyrias.
James MF, Hift RJ. Br J Anaesth. 2000 Jul; 85(1):143-53.
|
10928003 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Alfentanil · Rapifen 
Alfentanil · Rapifen 
Limifen 
Alfentanil 
Rapifen 
Alfentanil · Rapifen · Rapifen Intensive Care 
Alfentanil · Rapifen 
Alfentanil · Extempore N01AH02 Alfentanil · Rapifen 
Alfentanil · Rapifen 
Alfentanil · Rapifen 
Alfentanil Injection · Rapifen 
Rapifen 
Alfentanil · Rapifen 
Alfentanil 
Rapifen 
Alfentanil · Rapifen 
Rapifen 
Alfentanilo 
Alfentanil