Monograph

N02AA01 - Morphine

Not porphyrinogenic

Rationale

Several references as well as significant clinical experience indicate non-porphyrinogenicity.

Chemical description

Opioid analgesic often used in acute porphyric crisis. After conjugation with glucuronic acid to morphine-3-glucuronide it is eliminated by the kidneys. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use EPI-list: safe South African list: use French list: use Kalman, Bonkovsky: safe Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction.Biochem Biophys Acta 543:313, 1978: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: probably safe.

IPNet drug reports

Uneventful use reported in 41 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes N02A / N02AA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Diacetylmorfine · Diacetylmorfine 100 mg, poeder voor inhalatiedamp · Diacetylmorfine 150 mg, poeder voor inhalatiedamp · Diacetylmorfine 200 mg, poeder voor inhalatiedamp · Diacetylmorfine 75 mg, poeder voor inhalatiedamp · Diacetylmorfine HCl 3 g, poeder voor oplossing voor injectie · Maracex · Maracex 20 mg/ml oplossing voor injectie/infusie · Molnex · Molnex 10 mg/ml oplossing voor injectie · Molnex 20 mg/ml oplossing voor injectie · Morfine · Morfine HCl 10 mg/ml Focus, oplossing voor injectie/ infusie · Morfine HCl 100 mg/10ml Focus, oplossing voor injectie/ infusie · Morfine HCl 200 mg/10ml Focus, oplossing voor injectie/ infusie · Morfine HCl BModesto 10 mg/ml, oplossing voor injectie · Morfine HCl CF 10 mg/ml, oplossing voor injectie · Morfine HCl CF 20 mg/ml, oplossing voor injectie · Morfine HCl Expharma 10mg, tablet · Morfine HCl Expharma 20mg, tablet · Morfine HCl Expharma 30mg, tablet · Morfine HCl retard CF 10 mg, tabletten met verlengde afgifte · Morfine HCl retard CF 100 mg, tabletten met verlengde afgifte · Morfine HCl retard CF 30 mg, tabletten met verlengde afgifte · Morfine HCl retard CF 60 mg, tabletten met verlengde afgifte · Morfine HCl Teva 10 mg/ml, oplossing voor injectie · Morfine HCl Teva 20 mg/ml, oplossing voor injectie · Morfine Kalceks 10 mg/ml, oplossing voor injectie · Morfinesulfaat · Morfinesulfaat Aurobindo Retard 10 mg, tabletten met gereguleerde afgifte · Morfinesulfaat Aurobindo Retard 100 mg, tabletten met gereguleerde afgifte · Morfinesulfaat Aurobindo Retard 30 mg, tabletten met gereguleerde afgifte · Morfinesulfaat Aurobindo Retard 60 mg, tabletten met gereguleerde afgifte · Morfinesulfaat retard Teva 10 mg, tabletten met gereguleerde afgifte · Morfinesulfaat retard Teva 100 mg, tabletten met gereguleerde afgifte · Morfinesulfaat retard Teva 30 mg, tabletten met gereguleerde afgifte · Morfinesulfaat retard Teva 60 mg, tabletten met gereguleerde afgifte · Morfinesulfaat Sandoz 10 mg, tabletten · Morfinesulfaat Sandoz 20 mg, tabletten · Morfinesulfaat TioFarma 10 mg, tablet · Morfinesulfaat TioFarma 100 mg, tablet · Morfinesulfaat TioFarma 20 mg, tablet · MS Contin · MS Contin 10 mg, tabletten met verlengde afgifte · MS Contin 100 mg, tabletten met verlengde afgifte · MS Contin 15 mg, tabletten met verlengde afgifte · MS Contin 30 mg, tabletten met verlengde afgifte · MS Contin 5 mg, tabletten met verlengde afgifte · MS Contin 60 mg, tabletten met verlengde afgifte · Oramorph · Oramorph oplossing 10 mg / 5 ml, drank · Oramorph oplossing 10 mg/5 ml, drank · Oramorph oplossing 20 mg/ml, druppels voor oraal gebruik, oplossing · Oramorph Unit Dose Vial 10 mg/5 ml, drank · Oramorph Unit Dose Vial 100 mg/5 ml, drank · Oramorph Unit Dose Vial 30 mg/5 ml, drank · Sendolor · Sendolor 1 mg/ml, oplossing voor infusie · Sendolor 10 mg/ml, oplossing voor infusie · Sendolor 10mg/ml, oplossing voor injectie · Sendolor 1mg/ml, oplossing voor injectie · Sendolor 20 mg/ml, oplossing voor infusie · Sendolor 20mg/ml, oplossing voor injectie

Belgium

Morphine · Morphine HCl Sterop 10 mg/ml sol. inj. i.théc./s.c./i.v./p.dural/i.m. amp. · Morphine HCl Sterop 20 mg/ml sol. inj. i.théc./s.c./i.v./p.dural/i.m. amp. · Morphine HCl Sterop 30 mg/ml sol. inj. i.théc./s.c./i.v./p.dural/i.m. amp. · Morphine HCl Sterop 40 mg/ml sol. inj. i.théc./s.c./i.v./p.dural/i.m. amp. · Morphine Teva 10 mg compr. lib. modif. · Morphine Teva 100 mg compr. lib. modif. · Morphine Teva 30 mg compr. lib. modif. · Morphine Teva 60 mg compr. lib. modif. · Ms · Ms Direct 10 mg compr. enr. · Ms Contin · Ms Contin 10 mg compr. lib. prol. · Ms Contin 100 mg compr. lib. prol. · Ms Contin 30 mg compr. lib. prol. · Ms Contin 60 mg compr. lib. prol. · Oramorph · Oramorph 20 mg/ml sol. buv.

United Kingdom

Actimorph · Actimorph 10mg orodispersible tablets · Actimorph 1mg orodispersible tablets · Actimorph 2.5mg orodispersible tablets · Actimorph 20mg orodispersible tablets · Actimorph 30mg orodispersible tablets · Actimorph 5mg orodispersible tablets · Depodur · Depodur 10mg/1ml suspension for injection vials · Filnarine SR · Filnarine SR 100mg tablets · Filnarine SR 10mg tablets · Filnarine SR 200mg tablets · Filnarine SR 30mg tablets · Filnarine SR 60mg tablets · Morcap SR · Morcap SR 100mg capsules · Morcap SR 20mg capsules · Morcap SR 50mg capsules · Morphgesic SR · Morphgesic SR 100mg tablets · Morphgesic SR 10mg tablets · Morphgesic SR 30mg tablets · Morphgesic SR 60mg tablets · Morphine · Morphine 0.1% gel · Morphine 0.2% gel · Morphine 100mg modified-release tablets · Morphine 10mg modified-release tablets · Morphine 2% gel · Morphine 200mg capsules · Morphine 200mg modified-release tablets · Morphine 30mg capsules · Morphine 30mg modified-release tablets · Morphine 5mg/5ml nebuliser liquid ampoules · Morphine 60mg capsules · Morphine 60mg modified-release tablets · Morphine hydrochloride 1.5mg/5ml oral solution · Morphine hydrochloride 10mg/5ml oral solution · Morphine hydrochloride 1mg/1ml solution for injection ampoules · Morphine hydrochloride 25mg/5ml oral solution · Morphine hydrochloride 30mg suppositories · Morphine hydrochloride 5mg/5ml oral solution · Morphine sulfate 1.5mg/5ml oral solution · Morphine sulfate 100mg/10ml solution for injection ampoules · Morphine sulfate 100mg/50ml solution for infusion pre-filled syringes · Morphine sulfate 10mg/10ml solution for injection ampoules · Morphine sulfate 10mg/10ml solution for injection pre-filled syringes · Morphine sulfate 10mg/1ml solution for injection pre-filled syringes · Morphine sulfate 10mg/2ml solution for injection ampoules · Morphine sulfate 10mg/50ml solution for infusion pre-filled syringes · Morphine sulfate 120mg/120ml infusion bags · Morphine sulfate 120mg/60ml solution for infusion vials · Morphine sulfate 1g/1litre infusion bags · Morphine sulfate 1mg/1ml solution for injection ampoules · Morphine sulfate 1mg/20ml solution for infusion pre-filled syringes · Morphine sulfate 1mg/25ml solution for infusion pre-filled syringes · Morphine sulfate 2.5mg/25ml solution for injection pre-filled syringes · Morphine sulfate 2.5mg/50ml solution for infusion vials · Morphine sulfate 2.5mg/5ml oral solution · Morphine sulfate 2.5mg/5ml solution for injection ampoules · Morphine sulfate 20mg/2ml solution for injection ampoules · Morphine sulfate 250mg/250ml infusion bags · Morphine sulfate 2mg/10ml solution for injection ampoules · Morphine sulfate 2mg/2ml solution for injection ampoules · Morphine sulfate 2mg/5ml oral solution · Morphine sulfate 2mg/5ml solution for injection ampoules · Morphine sulfate 300mg/10ml solution for injection ampoules · Morphine sulfate 30mg/30ml solution for infusion vials · Morphine sulfate 3mg/50ml solution for infusion vials · Morphine sulfate 40mg/1ml solution for injection ampoules · Morphine sulfate 40mg/5ml oral solution · Morphine sulfate 4mg/10ml solution for injection ampoules · Morphine sulfate 4mg/20ml solution for injection pre-filled syringes · Morphine sulfate 500mg/10ml solution for injection ampoules · Morphine sulfate 500mg/500ml infusion bags · Morphine sulfate 500micrograms/5ml oral solution · Morphine sulfate 50mg/1ml solution for injection ampoules · Morphine sulfate 50mg/25ml solution for injection ampoules · Morphine sulfate 50mg/50ml solution for infusion pre-filled syringes · Morphine sulfate 50mg/50ml solution for infusion vials · Morphine sulfate 50mg/5ml oral solution · Morphine sulfate 50mg/5ml solution for injection ampoules · Morphine sulfate 5mg/10ml solution for injection ampoules · Morphine sulfate 5mg/1ml solution for injection ampoules · Morphine sulfate 5mg/25ml solution for infusion pre-filled syringes · Morphine sulfate 5mg/5ml solution for injection ampoules · Morphine sulfate 60mg suppositories · Morphine sulfate 60mg/30ml solution for injection vials · Morphine sulfate 750mg suppositories · Morphine sulfate 800micrograms/20ml solution for injection pre-filled syringes · Morphine 0.1% in Intrasite gel · Morphine 0.2% in Intrasite gel · Morphine hydrochloride · Morphine hydrochloride 100mg/5ml oral solution · Morphine hydrochloride 10mg suppositories · Morphine hydrochloride 10mg/10ml solution for injection pre-filled syringes · Morphine hydrochloride 15mg suppositories · Morphine hydrochloride 15mg/5ml oral solution · Morphine hydrochloride 20mg/5ml oral solution · Morphine hydrochloride 50mg/50ml solution for infusion pre-filled syringes · Morphine hydrochloride 50mg/5ml oral solution · Morphine hydrochloride 5mg/5ml solution for injection ampoules · Morphine hydrochloride powder · Morphine sulfate · Morphine sulfate 100mg suppositories · Morphine sulfate 100mg/100ml infusion bags · Morphine sulfate 100mg/50ml solution for infusion vials · Morphine sulfate 10mg suppositories · Morphine sulfate 10mg/10ml solution for injection Minijet pre-filled syringes · Morphine sulfate 10mg/1ml solution for injection ampoules · Morphine sulfate 10mg/5ml oral solution · Morphine sulfate 10mg/5ml oral solution unit dose vials sugar free · Morphine sulfate 15mg suppositories · Morphine sulfate 15mg/1ml solution for injection ampoules · Morphine sulfate 1g/1litre solution for infusion bottles · Morphine sulfate 1g/25ml solution for injection pre-filled syringes · Morphine sulfate 1g/5ml oral solution · Morphine sulfate 1mg/5ml oral solution · Morphine sulfate 2.5mg suppositories · Morphine sulfate 200micrograms/1ml solution for injection pre-filled syringes · Morphine sulfate 20mg suppositories · Morphine sulfate 20mg/10ml solution for injection pre-filled syringes · Morphine sulfate 20mg/1ml solution for injection ampoules · Morphine sulfate 20mg/5ml oral solution · Morphine sulfate 2mg/20ml solution for injection pre-filled syringes · Morphine sulfate 3.35mg/5ml oral solution · Morphine sulfate 30mg suppositories · Morphine sulfate 30mg/1ml solution for injection ampoules · Morphine sulfate 30mg/5ml oral solution · Morphine sulfate 3mg/5ml oral solution · Morphine sulfate 500mg/500ml infusion bottles · Morphine sulfate 50mg suppositories · Morphine sulfate 5mg suppositories · Morphine sulfate 5mg/5ml oral solution · Morphine sulfate 60mg/2ml solution for injection ampoules · Morphine sulfate 60mg/5ml oral solution · Morphine sulfate 75mg/5ml oral solution · Morphine sulfate 80mg/5ml oral solution · Morphine sulfate powder · MST Continus · MST Continus 100mg tablets · MST Continus 10mg tablets · MST Continus 15mg tablets · MST Continus 200mg tablets · MST Continus 30mg tablets · MST Continus 5mg tablets · MST Continus 60mg tablets · MST Continus suspension · MST Continus suspension 100mg granules sachets · MST Continus suspension 200mg granules sachets · MST Continus suspension 20mg granules sachets · MST Continus suspension 30mg granules sachets · MST Continus suspension 60mg granules sachets · MXL · MXL 120mg capsules · MXL 150mg capsules · MXL 200mg capsules · MXL 30mg capsules · MXL 60mg capsules · MXL 90mg capsules · Oramorph · Oramorph 100mg/5ml oral solution unit dose vials · Oramorph 10mg/5ml oral solution · Oramorph 10mg/5ml oral solution unit dose vials · Oramorph 20mg/ml concentrated oral solution · Oramorph 30mg/5ml oral solution unit dose vials · Rhotard Morphine SR · Rhotard Morphine SR 100mg tablets · Rhotard Morphine SR 10mg tablets · Rhotard Morphine SR 30mg tablets · Rhotard Morphine SR 60mg tablets · Sendolor · Sendolor 100mg/100ml infusion bags · Sevredol · Sevredol 10mg tablets · Sevredol 10mg/5ml oral solution · Sevredol 20mg tablets · Sevredol 20mg/ml concentrated oral solution · Sevredol 50mg tablets · Zomorph · Zomorph 100mg modified-release capsules · Zomorph 10mg modified-release capsules · Zomorph 200mg modified-release capsules · Zomorph 30mg modified-release capsules · Zomorph 60mg modified-release capsules

Denmark

Contalgin · Contalgin Uno · Depolan · Doltard · Malfin · Morfin · Morfin "Abcur" · Morfin "DAK" · Morfin "DLF" · Morfin "EQL Pharma" · Morfin "SAD" · Morfinsulfat · Morfinsulfat "Nordic Prime" · Oramorph · Sendolor

Norway

Contalgin Uno specific · Dolcontin · Malfin · Morfin · Morfin Abcur · Morfin Epidural · Morfin NAF · Morfin Orifarm · Morfin SA · Morfine HCI centrafarm u/kons · Oramorph · Sevre-Long

Poland

Autostrzykawka Morfina Przeciwko Bólowi · Doltard · Maracex · Morphine Kalceks · Morphini sulfas WZF · Morphini sulfas WZF 0,1% Spinal · MST Continus · Oramorph · Sevredol · Vendal retard

Luxembourg

MORPHINE · MORPHINE STEROP · MS CONTIN · MS DIRECT · ORAMORPH · Sendolor

Iceland

Contalgin · Contalgin Uno · Morfin · Morfin Abcur · Morphine · Morphine sulfate Kalceks

Finland

Molnex · Morphin · Oramorph · Sendolor

Latvia

Morfina · Morfina hidrohlorids-Kalceks · Morphin · Morphin SANITAS · Vendal · Vendal retard

Serbia

Morfin hidrohlorid · Morfin hidrohlorid Alkaloid® · Oramorph · Oramorph®

Acute Porphyria Drug Database

Monograph