Acute Porphyria Drug Database

Monograph

N02AA03 - Hydromorphone
Propably not porphyrinogenic
PNP

Rationale
Opioid. References state non-porphyrinogenicity.
Chemical description
Opioid analgesic metabolized to a large extent and excreted in urine in conjugated form. Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction.Biochem Biophys Acta 543:313, 1978: safe. Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: probably safe.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.

Similar drugs
Explore alternative drugs in similar therapeutic classes N02A / N02AA or go back.

Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.
Netherlands
Hydagelan · Hydagelan 10 mg/ml oplossing voor injectie/infusie · Hydagelan 2 mg/ ml oplossing voor injectie/infusie · Hydagelan 20 mg/ml oplossing voor injectie/infusie · Hydagelan 50 mg/ml oplossing voor injectie/infusie · Hydromorfonhydrochloride · Hydromorfonhydrochloride Kalceks 10 mg/ml oplossing voor injectie/infusie · Hydromorfonhydrochloride Kalceks 2 mg/ml oplossing voor injectie/infusie · Hydromorfonhydrochloride Kalceks 20 mg/ml oplossing voor injectie/infusie · Hydromorfonhydrochloride Kalceks 50 mg/ml oplossing voor injectie/infusie · Palladon · Palladon injectie 10 mg/ml, oplossing voor injectie of infusie · Palladon injectie 2 mg/ml, oplossing voor injectie of infusie · Palladon injectie 50 mg/ml, oplossing voor injectie of infusie · Palladon injectie, 50 mg/ml, oplossing voor injectie of infusie · Palladon-IR · Palladon-IR capsules 1,3 mg, capsules · Palladon-IR capsules 2,6 mg, capsules · Palladon-SR · Palladon-SR capsule 16 mg, capsules met verlengde afgifte · Palladon-SR capsule 24 mg, capsules met verlengde afgifte · Palladon-SR capsule 4 mg, capsules met verlengde afgifte · Palladon-SR capsule 8 mg, capsules met verlengde afgifte
Belgium
Palladone · Palladone Slow Release 4 mg gél. lib. prol. · Palladone Slow Release 8 mg gél. lib. prol. · Palladone Immediate · Palladone Immediate Release 2.6 mg gél.
United Kingdom
Hydromorphone · Hydromorphone 10mg/1ml solution for injection ampoules · Hydromorphone 20mg/1ml solution for injection ampoules · Hydromorphone 50mg/1ml solution for injection ampoules · Hydromorphone 5mg/5ml oral solution · Palladone · Palladone 1.3mg capsules · Palladone 10mg/1ml solution for injection ampoules · Palladone 2.6mg capsules · Palladone 20mg/1ml solution for injection ampoules · Palladone 2mg/1ml solution for injection ampoules · Palladone 50mg/1ml solution for injection ampoules · Palladone SR · Palladone SR 16mg capsules · Palladone SR 24mg capsules · Palladone SR 2mg capsules · Palladone SR 4mg capsules · Palladone SR 8mg capsules
Denmark
Hydofon · Hydromorphonhydrochlorid · Hydromorphonhydrochlorid "Kalceks" · Palladon
Norway
Hydofon · Palladon · Palladone SR
Luxembourg
Hydromorphon · Hydromorphon-hameln · PALLADONE · PALLADONE IMMEDIATE RELEASE-2,6 · PALLADONE SLOW RELEASE
Finland
Hydofon · Hydromorphone Kalceks · Palladon
Latvia
Hydromorphone · Hydromorphone Kalceks
 
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