Acute Porphyria Drug Database

Monograph

N02BA01 - Acetylsalicylic Acid
Not porphyrinogenic
NP

Rationale
Insignificant CYP 2C9 metabolism. Repeatedly experienced to be safe in acute porphyria. Several references state non-porphyrinogenicity.
Chemical description
Light analgesic, inhibitor of prostaglandin synthesis. Metabolized by conjugation with glycine. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use EPI-list: safe South African list: use French list: use Kalman, Bonkovsky: safe Merck Index: safe Eales L: Porphyria and the dangerous life-threatening drugs. S Afr Med J 56:914,1979: safe Swedish experience (n=32): tolerated.
IPNet drug reports
Uneventful use reported in 90 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes N02B / N02BA or go back.
Tradenames
This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.


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