N02BF01 - Gabapentin |
Probably not porphyrinogenic |
PNP |
Rationale
Not metabolised.
Chemical description
Water-soluble methyl cyclohexane acetic acid structural analogue to GABA, used in additional treatment in all types of partial epilepsy. No first-pass metabolism, excreted in unchanged form in urine.
Personal communication
Andersson C, patient report: Tolerated (n=1).
Used in porphyria wards (Sweden).
IPNet drug reports
Uneventful use reported in 25 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Gabapentin treatment of seizures in acute intermittent porphyria.
Tatum WO, Zachariah SB. Neurology. 1995 Jun; 45(6):1216-7.
|
7783893 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 4. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Gabapentine · Neurontin 
Gabapentine · Neurontin 
Gabapentine · Neurontin 
Gabapentina · Neurontin 
Gabagamma · Garlimo · Garonoan · Gordius · Grimodin · Neurontin 
Gabapentin · Neurontin 
Gabagamma · Gabalept · Gabapentin · Gabapentina · Gabaran · Grimodin 
Gabapentin · Neurontin 
Gabapentin · Neurontin 
Gabafarm · Gabamed · Gabapenstad · Gabapentin · Gabaprozap · Gabaratio · Gabatifin · Neurisol · Neurontin 
Anivo · Delarit · GabaLiquid GeriaSan · Gabapentin · Nelakap · Neurisol · Neurontin · Shaktatin 
GabaLiquid GeriaSan · Gabapentin · Neurisol · Neurontin · Shaktatin 
Gabapentin · Neurontin 
Gabapentin · Neurontin · Nugabin · Nupentin 
Gabapentin · Gralise · Neurontin 
Gabapentin · Neurontin 
Neurontin 
Gabagen · Gabapenstad · Gabapentin · Neurisol · Neurontin 
Gabapentin · Gabrion · Neurisol · Neurontin 
Gabagamma · Gabapentin · Gabapentina · Gabapentine · Gamanea · Garlimo · Gordius · Grimodin · Neurontin 
Gabagamma · Gabapentin · Garlimo · Gasenlan · Gordius · Neurontin 
Gabagamma · Gabapentin · Gamanea · Garlimo · Neurontin 
Gabagamma 
Katena · Neurontin 
Gabapentin · Neurontin 
Gabagamma · Gabanox · Gabapentin · Gordius · Grimodin · Neurontin 
Gabapentin · Gralise · Neurontin 
Gabapentine 
Gabapentina 
Gabapentin