N05AD01 - Haloperidol |
Probably not porphyrinogenic |
PNP |
Rationale
No data pointing to CYP-induction. Repeatedly used in acute porphyria without ill effects. Several references state non-porphyrinogenicity.
Chemical description
Butyrphenone low-dose neuroleptic used in psychotic conditions (e.g. in paranoia), also in childhood. Used in confusion states in elderly and against vomiting, e.g. in radiation sickness. Extensively metabolized, CYPs probably involved. No data pointing to CYP-inducing properties.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Drug reference publications | ||
| 1. | Martindale: The complete drug reference. Pharmaceutical Press.
Sweetman SC, editor.
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| Porphyria Drug Lists | ||
| 2. | Australian List
Australian Porphyria Association No longer maintained
|
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| 3. | French List
Centre Français des Porphyries
|
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| 4. | EPI List
European Porphyria Initiative No longer maintained
|
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| 5. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Haldol · Haldol decanoas · Haloperidol 
Haldol · Haldol Decanoas 
Haldol · Haldol Decanoas 
Haloperidol 
Haloperidol · Haloperidol Decanoat 
Aloperidolo · Haldol · Haldol Decanoas · Serenase 
Haloperidol 
Haldol · Haldol Decanoas 
Dozic · Haldol · Haldol Decanoate · Halkid · Haloperidol · Serenace 
Haloperidol · Serenase 
Extempore N05AD01 Haloperidol · Haldol · Haldol Decanoas · Haloperidol · Serenase 
Haldol · Haloperidol 
Decaldol · Haloperidol 
Apracal · Haloperidol 
Haldol · Haldol Conc · Haloperidol · Serenace 
Haloxen · Manace · Myung Haloperidol 
Haloperidol 
Haldol · Haldol Decanoas 
Haldol 
Serenase 
Decaldol · Haldol · Haldol Decanoas · Haloperidol · Heloper l.a. 
Haloperidol 
Haloperidol 
Haloperidol 
Haloperidol 
Haldol · Haloperidol · Haloperidol Forte 
Haloperidol 
Dolpin · Dozic · Fortunan · Haldol · Haloperidol · Haloperidol component of vesalium · Kentace · Keselen · Serenace 
Haloperidol