A07DA03 - Loperamide

Probably not porphyrinogenic

Rationale

Synthetic opiate, some systemic absorption takes place. Probably CYP-metabolised. No data pointing to CYP-induction. Two references state non-porphyrinogenicity.

Chemical description

Synthetic opiate used in diarrhoea. Metabolized by oxidative N-demethylation. No data given on CYP-interaction.

IPNet drug reports

Uneventful use reported in 17 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes A07D / A07DA or go back.

References

#	Citation details	PubMed ID
Porphyria Drug Lists
1.	French List Centre Français des Porphyries
2.	South African List Porphyria South Africa No longer maintained

Tradenames

Show more details and information about the listed tradenames

capsules Loperamide · Imodium · Loperamide

Imodium · Loperamide

Abeclin · Diarfin · Elissan · Fortasec · Loperamida · Loperan · Lopestop · Salvacolina · Sindiar

Enterobene · Imodium · Lopacut · Lopedium · Loperamide

Diarstop · Dissenten · Imodium · Lopemid · Loperamide · Teicoplanina

Clorhidrat Loperamida · Enterium · Imodium · Lopedium · Lopemidol · Loperamid · Loperamida · Loprex · Loprid · Tammex

Imodium · Loperam-X · Loperamid

. · Arret · Bell's Diarrhoea Relief · Diah-Limit · Diaquitte · Diareze Diarrhoea Relief · Diarrhoea Relief · Diasorb · Diocalm · Diocalm Ultra · Diocaps · Dioraleze · Galpharm Diarrhoea Relief · Galpharm Loperamide · Imodium · Imodium Classic · Imodium IBS Relief · Imodium Instants · Imodium LiquiCaps · Imodium Original · Imodium SoftGels · Lloydspharmacy DiaFix · Loperamide · Loritax · Norimode · Normaloe · Numark Diarrhoea Relief · Numark Diarrhoea Relief Instants · Superdrug Loperamide