Acute Porphyria Drug Database

Monograph

N06BA07 - Modafinil
Propably not porphyrinogenic
PNP

Rationale
Probably only insignificant CYP-metabolism. Weak CYP-inducer in vitro.
Chemical description
Narcotic psychostimulant used in treatment of narcolepsy. In vitro data demonstrate that modafinil is not metabolized to any large extent by CYPs. Inducer in vitro of CYPs 1A2, 2B6 and 3A4 in the liver. Inhibitor in vitro of CYPs 2C9 and 2C19.

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Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.
Netherlands
Aspendos · Aspendos 100 mg, tabletten · Modafinil · Modafinil 200 mg Focus, tabletten · Modafinil Aurobindo 100 mg, tabletten · Modafinil Emona 100 mg tabletten · Modafinil Emona 200 mg tabletten · Modafinil Mylan 100 mg, tabletten · Modiodal · Modiodal 100 mg tabletten
Belgium
Provigil · Provigil 100 mg comp.
United Kingdom
Modafinil · Modafinil 100mg tablets · Modafinil 100mg/5ml oral solution · Modafinil 100mg/5ml oral suspension · Modafinil 200mg tablets · Modafinil 200mg/5ml oral solution · Provigil · Provigil 100mg tablets · Provigil 200mg tablets
Denmark
Modafinil · Modafinil "Orifarm" · Modafinil "Orion" · Modapram · Modiodal · Myldamo
Norway
Modiodal
Poland
Actimodan
Luxembourg
PROVIGIL
Iceland
Aspendos · Modiodal · Myldamo
Finland
Modafinil Orion
 
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