R03BA01 - Beclometasone |
Not porphyrinogenic |
NP |
Rationale
Inducer of CYP3A5. Probably insignificant absorption. Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
Halogenated corticosteroid in inhalation aerosol, used in treatment of asthma. Systemic exposure only of doses > 1500 µg/24 h (adults).
Personal communication
Used in porphyria ward (Sweden).
IPNet drug reports
Uneventful use reported in 12 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
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9554242 |
| 2. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Porphyria Drug Lists | ||
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
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| 4. | South African List
Porphyria South Africa No longer maintained
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| Other sources | ||
| 5. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
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Tradenames
Beclometason · Beclometasondipropionaat · Qvar · Soprobec 
Qvar 
Beclojet · Beclometasone · Beclometasone chi · Beclospin · Beclospray · Becotide · Bemedrex · Ecobec · Miflasone · Qvar 
Beclo-Asma · Becloforte · Becotide · Soprobec 
Beclometasone · Becloneb · Becotide · Clenil · Clenilexx · Prontinal 
Clenil jet · Soprobec 
Beclo · Qvar 
AeroBec 100 · AeroBec 50 · AeroBec Forte 250 · Asmabec 100 · Asmabec 250 · Asmabec 50 · Beclazone 100 · Beclazone 200 · Beclazone 250 · Beclazone 50 · Becloforte · Beclometasone · Beclometasone 100 · Beclometasone 200 · Beclometasone 400 · Beclu · Becodisks · Becotide · Becotide 100 · Becotide 200 · Becotide 50 · Clenil Modulite · Easyhaler Beclometasone · Filair 100 · Filair 50 · Filair Forte · Kelhale · Pulvinal Beclometasone Dipropionate · Qvar · Soprobec 
Aerobec · Beclomet · Beclometasondipropionat 
AeroBec · Beclomet · Becotide 
Aerobec · Beclomet 
Soprobec 
Beclometasona · Beclort · Beklocart · Eclosynt · Kelhale · Nabumex 
Aldecin · Atomide · Atomide Forte · Beclazone · BecloClear · Becloforte · Beclomethasone Diproprionate · Becospray · Becospray forte · Becotide · Becotide nebulising · Miflasone · Miflonide · Qvar · Respocort · Respocort Forte · Respocort Forte-S 
Beclo-Asma · Beclomet · Clenil 
Qvar 
Qvar 
Aerobec · Beclomet 
Beclomet 
Becloforte 
Qvar 
Becloforte · Becodisks · Becotide · Plibecot 
Beclomet · Ecobec · Soprobec