R03BA07 - Mometasone |
Not porphyrinogenic |
NP |
Rationale
Probably insignificant systemic exposure. Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
Glucocorticosteroid used (400-800 µg/d) in asthma. Not significantly absorbed from lung or gastrointestinal channel. Metabolised by CYP3A4.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| 2. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Porphyria Drug Lists | ||
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
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| 4. | South African List
Porphyria South Africa No longer maintained
|
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| Other sources | ||
| 5. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
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Tradenames
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex · Bronconex Acticap 
Asmanex 
Asmanex 
Asmanex 
Asmanex 
Asmanex · Bloctimo 
Asmanex