Monograph

R05DA04 - Codeine

Propably not porphyrinogenic

Rationale

Opioid substrate for 2D6 and 3A4. Several references consider it safe for use.

Chemical description

Opioide with analgetic and antitussive properties. Demetylated by CYP 2D6 and 3A4. Inhibitor of 2D6. EPI-list: safe South African list: use French list: authorized Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction. Biochem Biophys Acta 543:313, 1978: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: safe

IPNet drug reports

Uneventful use reported in 27 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes R05D / R05DA or go back.

Tradenames

This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Show more details and information about the listed tradenames

Code?nefosfaat 1A Pharma 10 mg, tabletten · Code?nefosfaat 1A Pharma 15 mg, tabletten · Code?nefosfaat 1A Pharma 20 mg, tabletten · Code?nefosfaat 1A Pharma 30 mg, tabletten · Code?nefosfaat Expharma 10 mg tabletten · Code?nefosfaat Expharma 15 mg tabletten · Code?nefosfaat Expharma 20 mg tabletten · Code?nefosfaat Expharma 30 mg tabletten · Code?nefosfaat Schmid 10 mg, tabletten · Code?nefosfaat Schmid 15 mg, tabletten · Code?nefosfaat Schmid 20 mg, tabletten · Code?nefosfaat Schmid 30 mg, tabletten · Codeïnefosfaat · Codeinefosfaat Teva 10 mg , tabletten · Codeinefosfaat Teva 15 mg, tabletten · Codeinefosfaat Teva 20 mg, tabletten · Natterman Melrosum Extra Sterk, stroop

Bronchodine 10 mg/5 ml sirop · Bronchosedal Codeine 9 mg/10 ml sirop · Codeinoform Qualiphar 10 mg/15 ml sirop · Codocalyptol 20 mg/15 ml sirop · Toularynx Codeine 11.49 mg/15 ml sirop

CODEISAN 1,26 mg/ml JARABE · CODEISAN 28,7 mg COMPRIMIDOS · FLUDAN CODE?NA 10 mg/ 5 ml SOLUCI?N ORAL · Fludan Codeína · HISTAVERIN 2 mg/ml JARABE · Notusin Solucion Oral · TOSEINA 2 mg/ml SOLUCION ORAL

CODEINA FOSFAT LPH 15 mg · CODEINA FOSFAT MCC 15 mg · CODEINA SLAVIA 15 mg · FOSFAT DE CODEINA BIOEEL 15 mg · FOSFAT DE CODEINA SINTOFARM 15 mg

Benylin Codeine · Bepro · Codeine · Codeine phosphate · Galcodine

Kodein · Kodein DAK · Kodein EQL Pharma · Kodein SAD · Kodein St?rk DAK

Kodein · Kodein st?rk dak

HERBAPini · Neoazarina · Sirupus Pini compositus

Bronchosedal Codeine · neo-Codion · neo-Codion Adultes · Toularynx Codeine

Acute Porphyria Drug Database

Monograph