R06AD52 - Promethazine, Combinations |
Possibly porphyrinogenic |
PSP |
Rationale
Promethazine is clinically observed to be unsafe (one report), stated to be safe in three references.
Chemical description
Antiemetic. The sedative effect of promethazine is lessened by caffeine. Its effect on motion sickness is enhanced by caffeine and ephedrine.
Personal communication
Schoenfeld: Observed to be extremely unsafe (promethazine).
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 4. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Tixylix Night Cough 
Lergigan 
Dhasedyl · Rhinathiol Promethazine 
Promethazine DM