Insufficient data on metabolism. Compare loratadine (R06AX13): "Metabolised by CYP3A4. Inducer of CYP3A4. Two references consider it safe. Clinical experience (Swedish) seems to point to non-porphyrinogenicity. "

Dibencycloheptene methylpiperadine antihistamine, also effective against itching in neurodermatitis. Main metabolite is the glucuronide conjugate of the drug. Is also excreted in unchanged form in faeces. Structural analogue to loratadine.