Possibly insignificant systemic exposure

Broadspectrum antibiotic in eye drops 5mg/mL (one drop, i.e. About 100 µg, every third hour for two days). EPI-list: unsafe Kalman, Bonkovski: unsafe South African list: avoid French list: interdit

Uneventful use reported in 3 patients with acute porphyria. One report of an acute porphyric attack in a susceptible male with AIP, but the attack was poorly documented. This report has therefore not been taken into account in the judgement of the porphyrinogenicity of chloramphenicol eye drops.