S01BA02 - Hydrocortisone |
Not porphyrinogenic |
NP |
Rationale
Probably insignificant systemic exposure. Substrate for CYPs 3A4, 3A7, 11 B2. Inducer and inhibitor (!) of CYP3A4. Several references stating non-porphyrinogenicity.
Chemical description
Glucocorticoid for eye application.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 4. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Softacor 
Hydrocortisone · Softacor · Stingesk 
Oftalmolosa Cusi Hidrocortisona · Softacort 
Softacort 
Cortivis · Sofacor 
Softacort 
Hydrocortison · Softacort 
Hydrocortisone · Hydrocortisone acetate · Softacort 
Softacort 
Ficortril · Softacort 
Softacort 
Softacort 
Hydrocortisyl 
Softacor 
Softacort 
Softacort 
Hydrocortisonum 
Hydrocortison · Softacort 
Softacort 
Hidrokortizonacetat · Softacort 
Ophthalmo-Hydrocortison · Softacort