Monograph
S01EC03 - Dorzolamide |
Propably not porphyrinogenic |
PNP |
Rationale
sulfonamide mainly distributed to erythrocytes. Probably insignificant systemic load. CYP metabolised, long duration of the final elimination phase.
Chemical description
sulfonamide used in eyedrops (20 mg/mL) to reduce the intraocular pressure in glaucoma. Converted to N-desethyl dorzolamide which binds to carbanhydrase. Reaches circulation in topical application but due to effective bindnding to erytrocyte carboanhydrases the plasma levels are very low. Metabolized by CYPs 3A3/4 and 2C9/10. A final elimination phase with a half time of four months takes place after termination of treatment.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Dorzolamide Aurobindo 20 mg/ml oogdruppels, oplossing · Dorzolamide Brown & Burk zonder conserveermiddel 20 mg/ml oogdruppels, oplossing in verpakking voor eenmalig gebruik · Dorzolamide CF 20mg/ml, oogdruppels, oplossing · Dorzolamide Viatris 20 mg/ml, oogdruppels, oplossing · Dorzostill 20 mg/ml, oogdruppels, oplossing · Odyral 20 mg/ml oogdruppels, oplossing in verpakking voor eenmalig gebruik · Trusmono conserveermiddelvrij 20 mg/ml oogdruppels, oplossing · TRUSOPT 20 mg/ml, oogdruppels, oplossing · TRUSOPT conserveermiddelvrij, oogdruppels, oplossing in flacon voor eenmalig gebruik 20 mg/ml 
Trusopt · Trusopt 2 % Unit Dose 20 mg/ml collyre sol. r?cip. unidose · Trusopt 20 mg/ml collyre sol. 
Arzolan 20 mg/ml Colirio en Solucion · Dimaz 20 mg/ml Colirio en Solucion · DORZOLAMIDA ARISTO 20 mg/ml COLIRIO EN SOLUCION · DORZOLAMIDA FARMALIDER 20 mg/ml COLIRIO EN SOLUCION · TRUSOPT 20 mg/ml COLIRIO EN SOLUCION 
Dorzoclar · Dorzolamide · Dorzonorm · Dorzostill · Trusopt · Zoliop 
DORZOLAMIDA ARENA 20 mg/ml · DORZOPT 20 mg/ml · TRUSOPT 20 mg/ml 
Dimaz · Dorzant · Dorzolamide · Eydelto · Trusopt · Vizidor 
Delazo · Dorzolamid Carefarm · Dorzolamid Hexal · Dorzolamid STADA · Dorzostill · Itoco · Odyral · Trusopt · Trusopt Ukonserveret · Trusopt-S Ukonserveret · Vizidor 
Trusopt 
Dorzolamid BIJON · Dorzoma Mono · Dorzostill · Nodofree · Nodom · Oftidor · Rozalin · Trusopt · Vizidor 
Dorzo-Vision · TRUSOPT 2% Unit Dose 
Dorzolamide Alvogen 
Itoco · Odyral · Trusopt · Vizidor 
Dorzolamide Actavis · Dorzolamide Elvim · Oftidor · Sakor · Trusopt 
Optodrop · Trusopt®
© NAPOS 2025