Monograph

S01ED51 - Timolol, Combinations

Propably not porphyrinogenic

Rationale

Probably insignificant hepatic exposure.

Chemical description

Timolol (betareceptor blocker) combined with carboanhydrase inhibitor dorzolamide, used as eyedrops to reduce the intraocular pressure in glaucoma. Dorzolamide is converted to N-desethyl dorzolamide which binds to carbanhydrase. Reaches circulation in topical application but due to effective binding to erytrocyte carboanhydrases the plasma levels are very low.

IPNet drug reports

Uneventful use reported in 2 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes S01E / S01ED or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Azarga · Azarga 10 mg/ml + 5 mg/ml oogdruppels, suspensie · Bekistan · Bekistan 50 microgram/ml + 5 mg/ml, oogdruppels, oplossing · Bimatoprost / Timolol · Bimatoprost/Timolol axunio 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Brown & Burk 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing in verpakking voor eenmalig gebruik · Bimatoprost/Timolol CF 0,3 mg/ml + 5 mg/ml, oogdruppels, oplossing · Bimatoprost/Timolol Genetic 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Genetic 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing in verpakking voor eenmalig gebruik · Bimatoprost/Timolol Mylan 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol OmniVision 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Rompharm 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Sandoz 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Teva 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Bimatoprost/Timolol Zentiva 0,3 mg/ml + 5 mg/ml, oogdruppels, oplossing · BISANTIM · BISANTIM 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Blizomit · Blizomit 10 mg/ml + 5 mg/ml oogdruppels, suspensie · Brimonidine / Timolol · Brimonidine/Timolol Blumont 2 mg/ml + 5 mg/ml oogdruppels, oplossing · Brinzolamide / Timolol · Brinzolamide/Timolol Accord 10 mg/ml + 5 mg/ml oogdruppels, suspensie · Brinzolamide/Timolol CF 10 mg/ml + 5 mg/ml, oogdruppels, suspensie · Brinzolamide/Timolol Mylan 10+5 mg/ml, oogdruppels, suspensie · Brinzolamide/Timolol Xiromed 10 mg/ml + 5 mg/ml oogdruppels, suspensie · Combigan · Combigan 2 mg/ml + 5 mg/ml, oogdruppels, oplossing · Cosopt · COSOPT 20 mg/ml + 5 mg/ml, oogdruppels, oplossing · COSOPT CONSERVEERMIDDELVRIJ, oogdruppels, oplossing in verpakking voor eenmalig gebruik 20 mg/ml + 5 mg/ml · Cosopt Conserveermiddelvrij, oogdruppels, oplossing, flacon voor eenmalig gebruik 20 mg/ml + 5 mg/ml · COSOPT Multidose conserveermiddelvrij 20 mg/ml + 5 mg/ml oogdruppels, oplossing · Dorzolamide + Timolol · Dorzolamide + Timolol Stulln 20 mg/ml + 5 mg/ml oogdruppels, oplossing · Dorzolamide + Timolol Stulln zonder conserveermiddel 20 mg/ml + 5 mg/ml oogdruppels, oplossing in verpakking voor éénmalig gebru · Dorzolamide / Timolol · Dorzolamide/Timolol Aurobindo 20/5 mg/ml, oogdruppels, oplossing · Dorzolamide/Timolol Viatris 20/5 mg/ml, oogdruppels, oplossing · Dualkopt · Dualkopt 20 mg/ml + 5 mg/ml, oogdruppels, oplossing · DuoTrav · DuoTrav 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Ecbirio · Ecbirio 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · FILIOP · FILIOP 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Fixaprost · Fixaprost 50 microgram/ml + 5 mg/ml oogdruppels, oplossing · Fixaprost 50 microgram/ml + 5 mg/ml, oogdruppels, oplossing in verpakking voor éénmalig gebruik · Ganfort · Ganfort, oogdruppels, oplossing · Ganzed · Ganzed 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Kivizidiale · Kivizidiale 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Latanoprost / Timolol · Latanoprost/Timolol Aurobindo 50 microgram/ml + 5 mg/ml, oogdruppels, oplossing · Latanoprost/Timolol Blumont 50 microgram/ml + 5 mg/ml, oogdruppels, oplossing · Latanoprost/Timolol Teva 50 microgram/ml + 5 mg/ml, oogdruppels, oplossing · Latanoprost/timolol Viatris 50 microgram/ml + 5 mg/ml oogdruppels, oplossing · Latanotim · Latanotim 50 microgram/ml + 5 mg/ml oogdruppels, oplossing · Taptiqom · Taptiqom 15 microgram/ml + 5 mg/ml oogdruppels, oplossing · Taptiqom 15 microgram/ml + 5 mg/ml oogdruppels, oplossing in verpakking voor eenmalig gebruik · Travitim-Opto · Travitim-Opto 40 microgram/ml + 5 mg/ml oogdruppels, oplossing in een verpakking voor eenmalig gebruik · Travoprost / Timolol · Travoprost Teva 40 microgram/ml + Timolol 5 mg/ml oogdruppels, oplossing · Travoprost/Timolol 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Travoprost/Timolol CF 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Travoprost/Timolol Viatris 40 microgram/ml + 5 mg/ml oogdruppels, oplossing · Vizilaticom · Vizilaticom 50 microgram/ml + 5 mg/ml oogdruppels, oplossing · Vizimaco · Vizimaco 0,3 mg/ml + 5 mg/ml oogdruppels, oplossing · Xalacom · Xalacom 50 microgram/ml + 5 mg/ml oogdruppels, oplossing

Belgium

Akistancomb · Akistancomb 50 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Azarga · Azarga 10 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Combigan · Combigan 2 mg - 5 mg collyre sol. flac. compte-gouttes · Cosopt · Cosopt 20 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Cosopt Sine Conservans 20 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Cosopt Unit Dose 20 mg/ml - 5 mg/ml collyre sol. récip. unidose · Dorzolamide / Timolol · Dorzolamide/Timolol EG 20 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Dualkopt · Dualkopt 20 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · DuoTrav · DuoTrav 40 µg/ml - 5 mg/ml collyre sol. · Filiop · Filiop 40 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Fixaprost · Fixaprost 50 µg/ml - 5 mg/ml collyre sol. pompe · Fixaprost 50 µg/ml - 5 mg/ml collyre sol. récip. unidose · Ganfort · Ganfort 300 µg/ml - 5 mg/ml collyre sol. · Ganfort 300 µg/ml - 5 mg/ml collyre sol. récip. unidose · Ganzed · Ganzed 0.3 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Kivizidiale · Kivizidiale 40 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Latanoprost / Timolol · Latanoprost-Timolol AB 50 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Latanoprost/Timolol EG 50 µg/ml - 5 mg/ml collyre sol. · Latanoprost/Timolol Pharmathen 50 µg/ml - 5 mg/ml collyre sol. pompe · Taptiqom · Taptiqom 15 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Taptiqom 15 µg/ml - 5 mg/ml collyre sol. récip. unidose · TensocViatris · TensocViatris 20 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Timolatears · Timolatears 0.05 mg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Travoprost / Timolol · Travoprost/Timolol EG 40 µg/ml - 5 mg/ml collyre sol. flac. compte-gouttes · Vizilaticom · Vizilaticom 50 µg/ml - 5 mg/ml collyre sol. pompe · Vizimaco · Vizimaco 0.3 mg/ml - 5 mg/ml collyre sol. récip. multidos. · Xalacom · Xalacom 50 µg/ml - 5 mg/ml collyre sol.

United Kingdom

Bimatoprost / Timolol · Bimatoprost 300micrograms/ml / Timolol 5mg/ml eye drops · Bimatoprost 300micrograms/ml / Timolol 5mg/ml eye drops 0.4ml unit dose preservative free · Bimatoprost 300micrograms/ml / Timolol 5mg/ml eye drops preservative free · Brimonidine / Timolol · Brimonidine 2mg/ml / Timolol 5mg/ml eye drops · Codimaz · Codimaz 20mg/ml / 5mg/ml eye drops · Combigan · Combigan eye drops · Cosopt · Cosopt 20mg/ml / 5mg/ml eye drops · Cosopt 20mg/ml / 5mg/ml eye drops 0.2ml unit dose preservative free · Cosopt iMulti 20mg/ml / 5mg/ml eye drops · Cosopt iMulti 20mg/ml / 5mg/ml eye drops preservative free · Dorzolamide · Dorzolamide 20mg/ml / Timolol 5mg/ml eye drops · Dorzolamide 20mg/ml / Timolol 5mg/ml eye drops 0.2ml unit dose preservative free · DuoTrav 40micrograms/ml / 5mg/ml eye drops · Eylamdo · Eylamdo 20mg/ml / 5mg/ml eye drops · Eyzeetan · Eyzeetan 0.3mg/ml / 5mg/ml eye drops · Eyzeetan 0.3mg/ml / 5mg/ml eye drops preservative free · Fixapost · Fixapost 50micrograms/ml / 5mg/ml eye drops 0.2ml unit dose · Ganfort · Ganfort 0.3mg/ml / 5mg/ml eye drops · Ganfort 0.3mg/ml / 5mg/ml eye drops 0.4ml unit dose · Glaucopt · Glaucopt 20mg/ml / 5mg/ml eye drops 0.166ml unit dose preservative free · Latanoprost / Timolol · Latanoprost 50micrograms/ml / Timolol 5mg/ml eye drops · Medox · Medox 50micrograms/ml / 5mg/ml eye drops · Taptiqom · Taptiqom 15micrograms/ml / 5mg/ml eye drops 0.3ml unit dose · Tidomat · Tidomat 20mg/ml / 5mg/ml eye drops · Travoprost / Timolol · Travoprost 40micrograms/ml / Timolol 5mg/ml eye drops · Visublend · Visublend 0.3mg/ml / 5mg/ml eye drops · Vizidor Duo · Vizidor Duo 20mg/ml / 5mg/ml eye drops · Vizilatan Duo · Vizilatan Duo eye drops · Xalacom · Xalacom eye drops

Denmark

Azarga · Bimatoprost / Timolol · Bimatoprost/Timolol "Pharmathen" · Bimatoprost/Timolol "Stada" · Bimatoprost/Timolol "Zentiva" · Bimatoprost/Timolol Zentiva · Bitifrin · Brimonidine / Timolol · Brimonidine/Timolol "Stada" · Brimonidintartrat/Timolol "DOC Generici" · Brimonidintartrat/Timolol "Viatris" · Brinzolamid / Timolol · Brinzolamid/Timolol "Medical Valley" · Brinzolamide / Timolol · Brinzolamide/Timolol "Zentiva" · Combigan · Cosopt · Cosopt iMulti Ukonserveret · Cosopt Multi Ukonserveret · Cosopt Ukonserveret · Costad · Dorlatim · Dorzolamid / Timolol · Dorzolamid/Timolol "Medical Valley" · Dorzolamid/Timolol "Misom Labs Limited" · Dorzolamid/timolol "Pharmathen" · Dorzolamid/Timolol "Sandoz" · Dorzolamide / Timolol · Dorzolamide/Timolol "Stada" · Duokopt · DuoTrav · Eltenodo · Filiop · Fixapost · Fixopost · Galya · Ganfort · Ganzed · Jokath · Kivizidiale · Latacomp · Latanomol · Latanoprost / Timolol · Latanoprost/Timolol "Nordic Prime" · Latanoprost/Timolol "Pharmathen" · Latanostad comp · Lataxin · Latiotim · Lenigron · Oculokom · Taptiqom · Taptiqom sine · Tidimaz · Tirzopt · Travoprost / Timolol · Travoprost/Timolol "2care4" · Travoprost/Timolol "Medical Valley" · Travoprost/Timolol "Mylan" · Travoprost/Timolol "Stada" · Travoprost/Timolol "Viatris" · Vizidor Duo · Vizilaticom · Vizimaco · Xalcom · Zolbrinex

Norway

Azarga · Brinzolamid/Timolol Medical Valley · Brinzolamide/Timolol Zentiva · Combigan · Cosopt · Cosopt sine · Duokopt · DuoTrav · Fixapost · Fixopost · Fotil · Fotil Forte · Ganfort · Taptiqom · Taptiqom sine · Tavu · Travoprost / Timolol · Travoprost/Timolol Medical Valley · Xalcom · Xatabloc

Poland

Akistan Duo · Azarga · Bimaroz Duo · Bimatoprost / Timolol · Bimatoprost + Timolol Pharmabide · Bimatoprost Indoco · Bimifree Combi · Combigan · Cosopt · Cosopt PF · Cosopt PF Multi · Dorzolamide + Timolol Indoco · Dorzolamidum Timololum Stulln · Dropzol Tim · Duokopt · DuoTrav · Fixapost · Ganfort · Kivizidiale · Latacom · Latanoprost / Timolol · Latanoprost Timolol Genoptim · Nodofree Combi · Nodom Combi · Oftidorix · Rozacom · Rozaduo · Taptiqom · Taptiqom Multi · Tilaprox · Travoprost / Timolol · Travoprost + Timolol Medical Valley · Travoprost+Timolol Genoptim · Vizidor Duo · Vizilatan Duo · Vizimaco · Xalacom · Xaloptic Combi

Luxembourg

AZARGA · COMBIGAN · Cosopt · COSOPT Sine Conservans · COSOPT UNIT DOSE · Dorzolamide / Timolol · Dorzolamide/Timolol EG · Dualkopt · DUOTRAV · FILIOP · Fixaprost · Ganfort · Ganzed · Kivizidiale · Latanoprost / Timolol · Latanoprost/Timolol EG · Taptiqom · Timolatears · Travoprost / Timolol · Travoprost/Timolol EG · Vizilaticom · Vizimaco · Xalacom

Iceland

Arzotilol · Azarga · Bimatoprost / Timolol · Bimatoprost/Timolol Stada · Brinzolamide / Timolol · Brinzolamide/Timolol STADA · Combigan · Cosopt · Cosopt sine · Dorzolamide / Timolol · Dorzolamide/Timolol Alvogen · Dorzolamide/Timolol STADA · DUOKOPT · DuoTrav · Fixopost · Fotil Forte · Ganfort · Latanostad Comp · Taptiqom · Taptiqom sine · Travoprost / Timolol · Travoprost/Timolol Medical Valley · Travoprost/Timolol STADA · Xalcom

Finland

Azarga · Bimatoprost / Timolol · Bimatoprost/Timolol Stada · Bitifrin · Combigan · Cosopt · Cosopt Sine · Dorzolamid/Timolol Sandoz · Dorzolamide/Timolol Stada · Duokopt · Duotrav · Fixopost · Fotil · Fotil Forte · Ganfort · Glaukostad · Oftastad comp · Taptiqom · Taptiqom sine · Tidimaz · Travoprost / Timolol · Travoprost/Timolol STADA · Xalcom

Latvia

Amiptic · Amiptinon · Azarga · Bapiri · Bimatoprost / Timolol · Bimatoprost/Timolol Elvim · Bimatoprost/Timolol Mylan · Bimatoprost/Timolol Sandoz · Bimatoprost/Timolol Teva · Bitifrin · Bitimeco · Brinzolamide / Timolol · Brinzolamide/Timolol Accord · Brinzolamide/Timolol Stada · Brinzolamide/Timolol Zentiva · Combigan · Cosopt · Cosopt PF · Dorzolamide / Timolol · Dorzolamide/Timolol Actavis · Dorzolamide/Timolol ELVIM · Dotizolil · DuoTrav · Fixopost · Fotil · Ganfort · Latanoprost / Timolol · Latanoprost/Timolol ELVIM · Latira · Oftidorix · Taptiqom · Travoprost / Timolol · Travoprost/Timolol ELVIM · Travoprost/Timolol Polpharma · Travoprost/Timolol Stada · Travoprost/Timolol Viatris · Vizidorix · Xalacom

Serbia

AZARGA · AZARGA® · Bimadrop · Bimadrop® plus · Cosopt · Cosopt® · Cosopt® bez konzervansa · Doglam · Doglam® · Dorzoptic plus · Dorzoptic plus® · DUOKOPT · DUOKOPT® · DuoTrav · DuoTrav® · Fixalpost · Fixalpost® · Ganfort · Ganfort® · Glaumax · Latamed · OPTODROP-CO · Taptiqom · Taptiqom® · Xalacom · Xalacom®

Acute Porphyria Drug Database

Monograph