V03AF05 - Amifostine |
Not Porphyrinogenic |
NP |
Rationale
Non-CYP metabolism.
Chemical description
Organic thiophosphate used as a cytoprotective during treatment with cyclophosphamide combined with cisplatine in advanced ovarial cancer. Prodrug, rapidly metabolized by alcaline phosphatase to free phosphatase and the active free thiol.
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References
Tradenames
Ethyol 
Ethyol 
Amiforstin · Amifostin · Ethyol 
Ethyol 
Amifostine · Ethyol 
Amifostina 
Amifostine