Monograph
V03AF05 - Amifostine |
Not porphyrinogenic |
NP |
Rationale
Non-CYP metabolism.
Chemical description
Organic thiophosphate used as a cytoprotective during treatment with cyclophosphamide combined with cisplatine in advanced ovarial cancer. Prodrug, rapidly metabolized by alcaline phosphatase to free phosphatase and the active free thiol.
Similar drugs
Tradenames and packages
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United Kingdom
Ethyol · Ethyol 375mg powder for solution for infusion vials · Ethyol 500mg powder for solution for infusion vials
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