B01AA03 - Warfarin |
Probably Not Porphyrinogenic |
PNP |
Rationale
Metabolised by CYP2C9 but no data pointing to CYP-induction. Three references consider it safe.
Chemical description
Vitamin-K antagonist. Metabolized by CYP2C9. No data pointing to CYP-induction.
Personal communication
C.Andersson; patient reports: tolerated (n=3)
Ipnet drug reports
Uneventful use reported in 20 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| Porphyria Drug Lists | ||
| 2. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Coumadin · Jantoven 
Segavin · Warfarin 
Marevan 
Aldocumar 
01 · 02 · 03 · 04 · 05 · 06 · 07 · 08 · 09 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · Marfarin · Warfarin 
Coumadin 
Coumadin · Marevan · Warfarin 
Marevan · Warfarin 
Coumadin · Marevan · Waran · Warfarin 
Aldocumar · Marevan · Warfarin 
Warfin 
Warfar · Warfarina 
Coumadin · Marevan · Warfarin 
Marevan · Warfarin 
Warfarin 
Marevan 
Warfant · Warfarin 
Warfarin 
Marevan · Marevan Forte · Warfarin 
Orfarin · Warfarin · Warfarin–Grindeks 
Orfarin · Warfarin 
Marevan · Marevan Forte 
Farin 
Martefarin 
Marevan · Marivarin · Natrijev varfarinat 
Warfarin 
Choice 
Warfarine 
Warfarina 
Warfarin