A02BA04 - Nizatidine |
Probably not porphyrinogenic |
PNP |
Rationale
Less than 7% of an oral dose is metabolised (DrugBank). Alkylamines are mechanism-based inhibitors of CYPs 1A2, 2A6, 2C9, 2D6.
Chemical description
Aminoalkyl thiazol H2-receptor antagonist used in gastric acid hypersecretion. A smaller part is metabolized giving rise to sulfoxide (6%), N-oxide (5%) and desmethylnizatidine (7%). About 60% excreted in urine in unchanged form.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Drug reference publications | ||
| 1. | DrugBank Nizatidine.
Access Date: 2026-March-31 |
|
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Axid · Nizatidine · Zinga 
Axid 
Axid 
Axid · Nizatidine · Zinga 
Nizatidina 
Nizatidine