Monograph
C01CA07 - Dobutamine |
Not porphyrinogenic |
NP |
Rationale
Non-CYP metabolism. No data pointing to CYP-interaction. Four lists stating non-porphyrinogenicity.
Chemical description
Therapeutic characteristics
Synthetic catecholamine used in acute heart failure due to its inotropic effects on the heart. Given in infusion 0.25-1 g/l.
Metabolism and pharmacokinetics
Metabolized in tissues and in the liver. Conjugated to glucuronic acid and methylated by COMT. Excreted in urine within six hours as glucuronide conjugates.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
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Dobutamine CF 12,5 mg/ml, concentraat voor oplossing voor intraveneuze infusie · Dobutamine SUN 5 mg/ml oplossing voor infusie in voorgevulde spuit · Dobutamine-hameln 12,5 mg/ml steriel concentraat, concentraat voor oplossing voor infusie · Dobutamine-hameln 5 mg/ml i.v. infusievloeistof, oplossing voor infusie 
Dobutrexviatris · Dobutrexviatris 250 mg/20 ml sol. perf. (? diluer) i.v. flac. 
Dobutamina Hikma 12,5 mg/ml Concentrado Para Solucion Para Perfusion efg · DOBUTAMINA HOSPIRA 12,5 mg/ml CONCENTRADO PARA SOLUCION PARA PERFUSION EFG 
DOBUTAMINA ADMEDA 250 mg · DOBUTAMINA HAMELN 12,5 mg/ml · DOBUTAMINA HAMELN 5 mg/ml · DOBUTAMINA PANPHARMA 250 mg 
Dobutamine · Dobutrex · Posiject 
Dobutrex 
Dobutamin Hameln 
Dobutamin hameln · Dobutamin Sandoz · Dobutamine TZF 
Dobutamin Liquid Fresenius · Dobutrexviatris 
Dobutrex 
Dobutamin Hameln 
Dobutamin Admeda 250 · Dobutamine Panpharma
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