Polycyclic glucopeptide, not metabolised. No CYP affinity. One reference: use.

(To be edited, initial data ST OCT 04) Polycyclic glucopeptide antibiotic produced by Actinoplanes teichomyceticus, used in biomaterial associated infections with sepsis. Excreted by the kidneys in unchanged form. French list: use. South African list: use. Australian list: safe. See: Reimann et al. Effect of fusidic acid on hepatic cytochrome P450…Int J Clin Pharmacol Ther 1999; 37:562-6.