Monograph

J01DE01 - Cefepime

Propably not porphyrinogenic

Rationale

In greater part not metabolised. No clinical or experimental data pointing to CYP-interaction. Two references consider the drug safe or probably safe.

Chemical description

Parenterally administered cephalosporin used in serious pneumonia, serious infections outgoing from the lungs and serious intra abdominal infections. About 85% is excreted in unchanged form in urine. About 8% is excreted as primary or secondary metabilites. French list: use. South African list: use with caution. See: Jordan MC et al. Effect of cephalosporins.. (PMID 8140590) ( No induction of CYPs observed in animal study.)

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Tradenames

This list comprises raw data collected from different countries. In some cases, a more comprehensive list of available drug packages is included. Consequently, very similar terms may therefore appear multiple times. Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.

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Show more details and information about the listed tradenames

Cefepim Fresenius Kabi 1 g, poeder voor oplossing voor injectie of infusie · Cefepim Fresenius Kabi 2 g, poeder voor oplossing voor injectie of infusie · Cefepime Noridem 1 g, poeder voor oplossing voor injectie/infusie · Cefepime Noridem 2 g, poeder voor oplossing voor injectie/infusie · Cefepime-MIP 1 g, poeder voor oplossing voor injectie of infusie · Cefepime-MIP 2 g, Poeder voor oplossing voor injectie of infusie

Cefepim Fresenius Kabi 1 g sol. inj./perf. (pdr.) i.v. flac. · Cefepim Fresenius Kabi 2 g sol. inj./perf. (pdr.) i.v. flac. · Cefepime LDP-Laboratorios Torlan 1 000 mg sol. inj./perf. (pdr.) i.v./i.m. flac. · Cefepime LDP-Laboratorios Torlan 2 000 mg sol. inj./perf. (pdr.) i.v./i.m. flac. · Cefepime Noridem 1 g sol. inj./perf. (pdr.) i.v. flac. · Cefepime Noridem 2 g sol. inj./perf. (pdr.) i.v. flac.

Cefepima · CEFEPIMA ACCORD 1 g POLVO PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG · CEFEPIMA ACCORD 2 g POLVO PARA SOLUCION INYECTABLE Y PARA PERFUSION EFG · Cefepima Kabi 1g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima Kabi 2g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima ldp- Laboratorios Torlan 1 g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima ldp- Laboratorios Torlan 2 g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima mip 2 g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima Normon 1 g Polvo y Disolvente Para Solucion Inyectable y Para Pefusion efg · Cefepima Normon 2 g Polvo y Disolvente Para Solucion Inyectable y Para Perfusion efg · Cefepima Qilu 2 g Polvo Para Solucion Inyectable y Para Perfusion efg · Cefepima Sala 2 g Polvo Para Solucion Inyectable y Para Perfusion efg