J01DE01 - Cefepime |
Probably not porphyrinogenic |
PNP |
Rationale
In greater part not metabolised. No clinical or experimental data pointing to CYP-interaction. Two references consider the drug safe or probably safe.
Chemical description
Parenterally administered cephalosporin used in serious pneumonia, serious infections outgoing from the lungs and serious intra-abdominal infections. About 85% is excreted in unchanged form in urine. About 8% is excreted as primary or secondary metabolites.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Effect of the cephalosporin cefepime on hepatic drug metabolising enzyme activity in rats.
Jordan MC, Waller AR, et al. Toxicol Lett. 1994 Mar; 71(1):63-7.
|
8140590 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Cefepim · Cefepime 
Cefepim · Cefepime 
Cefepime 
Cefepima 
Cefepim · Cefepime 
Cefepima · Cefepime · Cepim · Cepimex 
Cefepima · Cefepime 
Cefepim · Cefepime 
Renapime 
Cefepim 
Cefepim · Extempore J01DE01 Cefepim · Maxipime 
Cefepim 
Cefepim · Cefepime 
Cefdeltime · Cefepima · Cefepime · Pimecef · Pozineg · Salapime 
Cefepime · Maxipime 
Cefepime · Cefevon 
Cefepime 
Cefepime 
Cefepim 
Bacteripime · Cefepima · Cefepime · Ilipim ip · Maxipime · Salapime 
Cefepime · Salapime 
Alphacef · Cefepime · Maxipime 
Cefepim · Cefepima · Cefim · Deltacef · Verapime 
Cefepim · Cefepime 
Alphacef · Cefepim · Deltacef · Maxipime 
Cefepim · Cefepime 
Renapime 
Cefepima 
Cefepime